New Products
  • X Water Purification System supplier
    Nymph X Water Purification System

    Multi-function; Space Saving; Great Adaptability to Water Source; Easy Operation; Produce Pure Water or Ultrapure Water with Stable and Eligible Quality.

  • Pyrogen-free Centrifuge Tube supplier
    Pyrogen-free Centrifuge Tube

    Pyrogen-free Centrifuge Tubes are widely used when culture cells.

  • USP Standard Gel Clot TAL
    USP Standard Gel Clot TAL in Test Tubes

    USP Standard Gel Clot Lyophilized Amebocyte Lysate in Test Tubes is the TAL reagent sealed under vacuum condition in a standard TAL reaction tube. Users add 0.2ml sample to dissolve the TAL reagent and do the test in a single step.

  • Gel Clot TAL Multiple Test
    Gel Clot LAL Reagent multi-test vial

    This is the most commonly used In Vitro method of endotoxin detection. The Gel Clot LAL Reagent multiple-test vial is simple and do not require an expensive instrument. 

  • Endotoxin Assay
    Endotoxin Assay Kit for Water and Dialysate (Gel Clot Assay)

    We supply Endotoxin Assay Kit for dialysis water and dialysate in gel clot method, kinetic turbidimetric method. The kits contain Control Standard Endotoxin, LAL reagent water and pyrogen-free sample bottles.

  • GC Endotoxin Test Kit
    Bioendo GC Endotoxin Test Kit (Gel Clot Assay)

    Bioendo GC Endotoxin Test Kit (Gel Clot Assay) combines Gel Clot TAL reagent and Control Standard Endotoxin in a kit, avoid the mismatched of TAL reagent and CSE.

Chromogenic LAL/TAL Assay

2019-05-10

Chromogenic LAL/TAL Assay

LAL/TAL reagent is the lyophilized amebocyte lysate which is extracted from the blue blood of Limulus polyphemus or Tachypleus tridentatus.

Endotoxins are amphiphilic lipopolysaccharides (LPS) located in the outer cell membrane of gram-negative bacteria. Parenteral products contaminated with pyrogens including LPS can lead to the development of fever, induction of inflammatory response, shock, organ failure and death in human. Therefore, countries around the world have formulated regulations, requiring that any drug product claiming to be sterile and non-pyrogenic should be tested prior to release. Gel-clot LAL/TAL assay was first developed for bacterial endotoxins test (i.e. BET). However, other more advanced methods of the LAL assay have emerged. And these methods will not only detect but also quantify the presence of endotoxins in a sample.

Apart from gel-clot technique, techniques for BET also contain the turbidimetric technique and the chromogenic technique.

Bioendo, dedicated to endotoxin detection, is the professional manufacturer to actually develop a chromogenic LAL/TAL assay. BioendoTM EC Endotoxin Test Kit (End-point Chromogenic Assay) provides a fast measurement for endotoxin quantification. We also provide BioendoTM KC Endotoxin Test Kit (Kinetic Chromogenic Assay) and incubation microplate reader ELx808IULALXH, which could ensure the reliability and efficiency of your experiments.

Xiamen Bioendo Technology Co., Ltd.

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