New Products
  • X Water Purification System supplier
    Nymph X Water Purification System

    Multi-function; Space Saving; Great Adaptability to Water Source; Easy Operation; Produce Pure Water or Ultrapure Water with Stable and Eligible Quality.

  • Pyrogen-free Centrifuge Tube supplier
    Pyrogen-free Centrifuge Tube

    Pyrogen-free Centrifuge Tubes are widely used when culture cells.

  • USP Standard Gel Clot TAL
    Gel Clot Lyophilized Amebocyte Lysate Single Test in Vial

    Gel Clot Lyophilized Amebocyte Lysate Single Test in Vial contains 0.2 endotoxin-specific Amebocyte Lysate which includes beta-glucan inhibitor in the formulation and will not react to beta-glucan. Furthermore, sample could be added to the vial directly. This means you don’t need to dilute Amebocyte Lysate at first, and could decide how many vials use each time to avoid waste.

  • Gel Clot TAL Multiple Test
    Gel Clot Lyophilized Amebocyte Lysate Multi-test Vial

    Gel Clot Lyophilized Amebocyte Lysate (LAL/TAL) Multi-test Vial is especially suitable for endotoxin detection in large amounts. Bioendo’s LAL/TAL reagent features strong resistance to interference and strong improvement for heat stability.

  • Endotoxin Assay
    Endotoxin Assay Kit for Water and Dialysate (Gel Clot Assay)

    Endotoxin Assay Kit for Water and Dialysate (Gel Clot Assay) assays the endotoxin in water or dialysate by using gel clot technique. Relating operation conforms to USP & EP. Endotoxin-specific Amebocyte Lysate is included by this kit, which will well avoid false positive reaction with Fungi (1,3)-β-D-glucan.

  • GC Endotoxin Test Kit
    Bioendo GC Endotoxin Test Kit (Gel Clot Assay)

    Bioendo GC Endotoxin Test Kit (Gel Clot Assay) includes Amebocyte Lysate, CSE and Water for BET. This will well avoid the mismatching between Amebocyte Lysate and CSE. The Kit is especially suitable for you when you need to do lots of endotoxin detection. Customized gel-clot endotoxin assay kit is also available upon your demand.

Chromogenic LAL/TAL Assay

2019-05-10

Chromogenic LAL/TAL Assay

LAL/TAL reagent is the lyophilized amebocyte lysate which is extracted from the blue blood of Limulus polyphemus or Tachypleus tridentatus.

Endotoxins are amphiphilic lipopolysaccharides (LPS) located in the outer cell membrane of gram-negative bacteria. Parenteral products contaminated with pyrogens including LPS can lead to the development of fever, induction of inflammatory response, shock, organ failure and death in human. Therefore, countries around the world have formulated regulations, requiring that any drug product claiming to be sterile and non-pyrogenic should be tested prior to release. Gel-clot LAL/TAL assay was first developed for bacterial endotoxins test (i.e. BET). However, other more advanced methods of the LAL assay have emerged. And these methods will not only detect but also quantify the presence of endotoxins in a sample.

Apart from gel-clot technique, techniques for BET also contain the turbidimetric technique and the chromogenic technique.

Bioendo, dedicated to endotoxin detection, is the professional manufacturer to actually develop a chromogenic LAL/TAL assay. BioendoTM EC Endotoxin Test Kit (End-point Chromogenic Assay) provides a fast measurement for endotoxin quantification. We also provide BioendoTM KC Endotoxin Test Kit (Kinetic Chromogenic Assay) and incubation microplate reader ELx808IULALXH, which could ensure the reliability and efficiency of your experiments.

Xiamen Bioendo Technology Co., Ltd.

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