New Products
  • X Water Purification System supplier
    Nymph X Water Purification System

    Multi-function; Space Saving; Great Adaptability to Water Source; Easy Operation; Produce Pure Water or Ultrapure Water with Stable and Eligible Quality.

  • Pyrogen-free Centrifuge Tube supplier
    Pyrogen-free Centrifuge Tube

    Pyrogen-free Centrifuge Tubes are widely used when culture cells.

  • USP Standard Gel Clot TAL
    Gel Clot Lyophilized Amebocyte Lysate Single Test in Vial

    Gel Clot Lyophilized Amebocyte Lysate Single Test in Vial contains 0.2 endotoxin-specific Amebocyte Lysate which includes beta-glucan inhibitor in the formulation and will not react to beta-glucan. Furthermore, sample could be added to the vial directly. This means you don’t need to dilute Amebocyte Lysate at first, and could decide how many vials use each time to avoid waste.

  • Gel Clot TAL Multiple Test
    Gel Clot Lyophilized Amebocyte Lysate Multi-test Vial

    Gel Clot Lyophilized Amebocyte Lysate (TAL) Multi-test Vial is especially suitable for endotoxin detection in large amounts. Bioendo’s TAL reagent features strong resistance to interference and strong improvement for heat stability.

  • Endotoxin Assay
    Endotoxin Assay Kit for Water and Dialysate (Gel Clot Assay)

    Endotoxin Assay Kit for Water and Dialysate (Gel Clot Assay) assays the endotoxin in water or dialysate by using gel clot technique. Relating operation conforms to USP & EP. Endotoxin-specific Amebocyte Lysate is included by this kit, which will well avoid false positive reaction with Fungi (1,3)-β-D-glucan.

  • GC Endotoxin Test Kit
    Bioendo GC Endotoxin Test Kit (Gel Clot Assay)

    Bioendo GC Endotoxin Test Kit (Gel Clot Assay) includes Amebocyte Lysate, CSE and Water for BET. This will well avoid the mismatching between Amebocyte Lysate and CSE. The Kit is especially suitable for you when you need to do lots of endotoxin detection. Customized gel-clot endotoxin assay kit is also available upon your demand.

LAL Reagent or TAL Reagent

2019-07-12

Limulus amebocyte lysate (LAL) or Tachypleus tridentatus (TAL) is an aqueous extract of blood cells from the horseshoe crab.

And endotoxins are hydrophobic molecules that are part of the lipopolysaccharide complex that forms most of the outer membrane of Gram-negative bacteria. Parenteral products contaminated with pyrogens can lead to serious consequences like fever, shock, organ failure, or even death.

LAL/TAL reagent could react with bacterial endotoxin and lipopolysaccharide (LPS). LAL’s endotoxin binding and clotting ability is what makes it so invaluable to our own pharmaceutical industry. And this is why LAL/TAL reagent could be employed to detect or quantify bacterial endotoxin.

Before the finding that LAL/TAL could be used to do bacterial endotoxins test, rabbits are employed to detect and quantify endotoxins in pharmaceutical products. Compared with RPT, BET with LAL/TAL reagent is rapid and efficient, and it is the popular way to do dynamic monitoring of endotoxin concentration in pharmaceutical industry, and so on.


Xiamen Bioendo Technology Co., Ltd.

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